ComBatic™ Antimicrobial Wound Lavage

The lavage is designed for use during wound cleansing, dressing changes, and wound bed preparation.

No. ComBatic^TM Lavage does not need to be rinsed off with another solution after use. It is designed to be used directly during wound cleansing and wound bed preparation.

After application, clinicians or caregivers should follow the wound-care protocol recommended by the healthcare provider, including appropriate dressing selection and frequency of dressing changes.

The frequency depends on the wound type, wound condition, level of exudate, presence of biofilm or infection signs, and the dressing-change schedule.

In many cases, ComBatic^TM Lavage can be used during dressing changes. This could range from twice daily to once daily, or less frequently, such as every other day, depending on the wound-care plan and clinical judgment.

This depends on the wound condition and treatment goal.

For wounds without visible signs of infection or biofilm, ComBatic^TM Lavage may be used as a cleansing solution to irrigate or gently clean the wound surface.

For wounds with suspected mild biofilm or localized microbial burden, ComBatic^TM Lavage may be applied to gauze and left in contact with the wound for approximately two minutes before continuing with standard wound care.

For wounds with heavier biofilm, slough, or higher microbial burden, ComBatic^TM Lavage may be applied using soaked sterile gauze and left in contact for up to five minutes. The process may be repeated as needed during wound bed preparation and debridement.

Yes. ComBatic^TM Lavage can be used as part of wound bed preparation and may support physical debridement. It can help soften and disrupt debris, biofilm-associated material and cleanse microbial contamination from the wound surface.

When debridement is required, it should be performed by a trained healthcare professional using appropriate clinical judgment and protocols.

Three years from the manufacturing date.

ComBatic^TM Antimicrobial Wound Lavage is a topical wound cleansing solution designed to help clean wounds, reduce microbial burden, and support a healthier wound environment.

It is powered by MHCombiotic's Combiotic^TM platform, which combines purified plant-derived small molecules with selected inorganic components to create a synergistic antimicrobial and antibiofilm effect.

Many traditional wound cleansers are based on antiseptic chemistries such as PHMB, iodine, silver, acid-based (HOCl, Acetic Acid, NaOCl, etc) or other broad-spectrum antimicrobial agents. These products can reduce microbial growth, but some may also affect healthy human cells, especially with repeated use or prolonged exposure.

ComBatic^TM Lavage was designed differently. It combines antimicrobial and wound-environment-supportive properties in one formulation. The goal is not only to reduce microbial burden, but also to support the wound-healing process by maintaining better compatibility with healthy tissue. It is also designed to avoid leaving behind unnecessary residues that may interfere with wound closure.

No. ComBatic^TM Lavage is not a conventional antibiotic. It is a non-antibiotic antimicrobial wound cleansing solution based on MHCombiotic's proprietary Combiotic^TM technology.

This is important because overuse of topical and systemic antibiotics can contribute to antimicrobial resistance. ComBatic^TM Lavage is designed to help manage microbial burden and biofilm without relying on traditional antibiotic mechanisms.

ComBatic^TM Lavage works through a multi-action mechanism. The formulation helps cleanse the wound surface and expose microorganisms that may be protected within the matrix and debris.

For more information about the core mechanism, visitors can refer to the Combiotic^TM Technology section.

A significant number of chronic wounds are contaminated with biofilm. Biofilm is one of the major reasons chronic wounds are difficult to heal.

Microorganisms inside biofilms are protected by a dense matrix, making them harder to remove and more tolerant to antimicrobial treatments.

Biofilm can maintain chronic inflammation, delay wound closure, and increase the risk of recurring infection.

A wound cleanser with antibiofilm activity can help improve wound bed preparation and support the healing process.

Wound debridement is the removal of dead tissue, slough, debris, and biofilm from the wound bed.

It is an important step in wound care because these materials can delay healing and create an environment where microorganisms can persist.

However, debridement can also temporarily expose deeper wound tissue and may increase local inflammation.

For this reason, infection control and wound-bed preparation are important before and during the debridement process.

ComBatic^TM Lavage helps prepare the wound bed by cleansing the wound surface, reducing microbial burden, disrupting wound debris and complex EPS matrices, and supporting local inflammation control.

The formulation includes a safe biosurfactant-based component that helps break down protective wound debris and the extracellular polymeric substance (EPS). This can make debridement more effective by helping loosen and remove harmful films, wound debris, and micro-colonies that may not be visible to the naked eye.

In addition, the plant-based components in ComBatic^TM Lavage are designed to support a more balanced wound environment and help control local inflammation, which can commonly occur during and after debridement. This combined wound-environment-supportive, antimicrobial, and antibiofilm approach helps promote cleaner, safer, and more effective wound bed preparation.

ComBatic^TM Lavage was developed with tissue compatibility as a key design priority.

Unlike some broad antiseptics that may affect both microbial and mammalian cells, ComBatic^TM Lavage is designed to reduce microbial burden while supporting compatibility with healthy tissue.

Safety and biocompatibility studies have been conducted to evaluate its suitability for topical wound-care use.

Yes. ComBatic^TM Lavage is designed for repeated use as part of routine wound care and dressing changes. The formulation has been developed to support wound cleansing while maintaining compatibility with healthy tissue. Use should follow the product instructions and the guidance of a healthcare professional.

ComBatic^TM Lavage is supported by extensive in-house testing and third-party laboratory studies. These include antimicrobial testing, antibiofilm studies, biocompatibility assessments, safety evaluations, and formulation performance studies.

The product is based on MHCombiotic's broader Combiotic^TM technology platform, which has been developed through extensive formulation screening, mechanistic studies, and preclinical evaluation.

No. ComBatic^TM Lavage can be used for wound cleansing and wound bed preparation where microbial burden, biofilm risk, or infection prevention is a concern.

It may be used in wounds with visible contamination, suspected biofilm, or increased microbial risk, as well as during routine dressing changes when antimicrobial cleansing is appropriate.

ComBatic^TM Lavage may be used in home-care settings. Patients should follow the instructions, product label, or health care professional.

For deep, severe, rapidly worsening, or highly painful wounds, patients should seek medical assessment before self-treating.

No, the solution is stable.